Article
Phenotypic comparison of four thalassemia model mice reconstructed from cryo-banked embryos.
Acta biologica Hungarica - 1 Dec 2013
Boonkusol D, Dinnyés A, Sa-Ardrit Mayurachat, Svasti Saovaros, Faisaikarm Tassanee, Vadolas J, Fucharoen Suthat, Kitiyanant Yindee
Abstract excerpt
A major clinical feature of patients with thalassemia is growth retardation due to anemia, therefore, the hematological parameters, weanling weight and post-weanling weight of pups obtained from vitrified warmed embryo transfers were studied for the first time in this report. Two-cell embryos of four transgenic (TG) thalassemic mouse lines (BKO, 654, E2, and E4) were produced by breeding four lines of TG...
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