Article
Stability of cryopreserved samples of mutant mice.
Biopreservation and biobanking - 1 Oct 2014
Ramin Michael, Bürger Antje, Hörlein Andreas, Kerkau Dagmar, von Walcke-Wulffen Vincent, Nicklas Werner, Schenkel Johannes
Abstract excerpt
Genetically modified animals are unique models with enormous scientific potential. Cryopreservation of pre-implantation embryos or of spermatozoa is a common approach to save those lines. The breeding of a line can be discontinued if a sufficient number of samples have been cryopreserved. To maintain the opportunity to recover a line, it is mandatory to assess the quality of the cryopreserved samples and to...
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