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Article

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

Human molecular genetics - 15 Apr 2014

Lyon Alison N, Pineda Ricardo H, Hao le Thi, Kudryashova Elena, Kudryashov Dmitri S, Beattie Christine E

Abstract excerpt

The actin-binding and bundling protein, plastin 3 (PLS3), was identified as a protective modifier of spinal muscular atrophy (SMA) in some patient populations and as a disease modifier in animal models of SMA. How it functions in this process, however, is not known. Because PLS3 is an actin-bindi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24271012
DOI: 10.1093/hmg/ddt595
PMCID: PMC3959813

Genes

PLS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24271012-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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