Article
Beyond high-dose methotrexate and brain radiotherapy: novel targets and agents for primary CNS lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Feb 2014
Ponzoni M, Issa S, Batchelor T T, Rubenstein J L
Abstract excerpt
BACKGROUND: While there has been significant progress in outcomes for patients diagnosed with primary central nervous system (CNS) lymphoma (PCNSL), survival rates will likely plateau with the current armamentarium of agents used to treat these patients. Moreover, given that PCNSL increasingly impacts an older population, a significant proportion of patients are not eligible for intensive therapies such as...
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