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Article

QM-MM simulations on p53-DNA complex: a study of hot spot and rescue mutants.

Journal of molecular modeling - 1 Dec 2013

Koulgi Shruti, Achalere Archana, Sharma Neeru, Sonavane Uddhavesh, Joshi Rajendra

Abstract excerpt

p53 is a transcription factor involved in the expression of a number of downstream genes in response to genotoxic stress. It is activated through post translation modifications in normal as well as cancerous cells. However, due to mutations occurring in p53 in cancer cells it is not able to perfo...

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Identifiers

PMID: 24253321
DOI: 10.1007/s00894-013-2042-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24253321-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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