Article
Detection of oseltamivir-resistant pandemic influenza A(H1N1)pdm2009 in Brazil: can community transmission be ruled out?
PloS one - 1 Jan 2013
Souza Thiago Moreno L, Resende Paola C, Fintelman-Rodrigues Natalia, Gregianini Tatiana Schaffer, Ikuta Nilo, Fernandes Sandra Bianchini, Cury Ana Luisa Furtado, Rosa Maria do Carmo Debur, Siqueira Marilda M
Abstract excerpt
Although surveillance efforts that monitor the emergence of drug-resistant strains of influenza are critical, systematic analysis is overlooked in most developing countries. We report on the occurrence of strains of pandemic influenza A(H1N1)pdm09 with resistance and decreased susceptibility to oseltamivir (OST) in Brazil in 2009, 2011 and 2012. We found 7 mutant viruses, 2 with the mutation S247N and other 5...
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