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Article

Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil.

Memorias do Instituto Oswaldo Cruz - 1 May 2013

Marx Camila, Gregianini Tatiana Schäffer, Lehmann Fernanda Kieling Moreira, Lunge Vagner Ricardo, Carli Silvia de, Dambrós Bibiana Paula, Tumioto Gabriela Luchiari, Seadi Claudete, Fonseca André Salvador Kazantzi, Ikuta Nilo

Abstract excerpt

The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study...

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Identifiers

PMID: 23778667
DOI: 10.1590/S0074-02762013000300021
PMCID: PMC4005575

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