Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene.

doi:10.1097/EDE.0000000000000030

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Article

Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene.

Epidemiology (Cambridge, Mass.) - 1 Jan 2014

Volk Heather E, Kerin Tara, Lurmann Fred, Hertz-Picciotto Irva, McConnell Rob, Campbell Daniel B

Abstract excerpt

BACKGROUND: Independent studies report association of autism spectrum disorder with air pollution exposure and a functional promoter variant (rs1858830) in the MET receptor tyrosine kinase (MET) gene. Toxicological data find altered brain Met expression in mice after prenatal exposure to a model air pollutant. Our objective was to investigate whether air pollution exposure and MET rs1858830 genotype interact to...

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PMID: 24240654
DOI: 10.1097/EDE.0000000000000030
PMCID: PMC4019012

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