Article
Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines.
Molecular cancer - 15 Nov 2013
Liu Wenyu, Jeganathan Gajan, Amiri Sohrab, Morgan Katherine M, Ryan Bríd M, Pine Sharon R
Abstract excerpt
BACKGROUND AND METHODS: Stem or progenitor cells from healthy tissues have the capacity to co-segregate their template DNA strands during mitosis. Here, we set out to test whether breast cancer cell lines also possess the ability to asymmetrically segregate their template DNA strands via non-random chromosome co-segregation, and whether this ability correlates with certain properties attributed to breast cancer...
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