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Article

Gene-wide tagging study of the effects of common genetic polymorphisms in the α subunits of the GABA(A) receptor on epilepsy treatment response.

Pharmacogenomics - 1 Nov 2013

Hung Chin-Chuan, Chen Pei-Lung, Huang Wan-Min, Tai John Jen, Hsieh Tsung-Jen, Ding Shih-Torng, Hsieh Yow-Wen, Liou Horng-Huei

Abstract excerpt

AIM: We aimed to identify the effect of SNPs in the α-subunits of GABAA receptors on epilepsy treatment outcomes by using a gene-wide tagging method. MATERIALS & METHODS: There were 720 epileptic patients included in the present study. A total of 136 tagging SNPs in GABRA1, GABRA2, GABRA3, GABRA4, GABRA5 and GABRA6 were genotyped by Illumina(®)GoldenGate(®) Genotyping platform. Clinical information, such as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24236484
DOI: 10.2217/pgs.13.158

Genes

GABRA1
GABRA2
GABRA3
GABRA4
GABRA5
GABRA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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