Surface induced collapse of Aβ1-42 with the F19A replacement following adsorption on a single walled carbon nanotube.

Abstract excerpt

Spontaneous adsorption of the Aβ peptide on the surface of a single-walled carbon nanotube, resulting in the prevention of its intrinsic propensity to form collapsed states, could be a plausible means to hinder the peptide's initial nucleation and self-assembly. We report here the effects of sharply reducing both aromatic and hydrophobic character within the peptide's central hydrophobic core on its free and...

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