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Article

The medaka mutation tintachina sheds light on the evolution of V-ATPase B subunits in vertebrates.

Scientific reports - 14 Nov 2013

Müller Claudia, Maeso Ignacio, Wittbrodt Joachim, Martínez-Morales Juan R

Abstract excerpt

Vacuolar-type H(+) ATPases (V-ATPases) are multimeric protein complexes that play a universal role in the acidification of intracellular compartments in eukaryotic cells. We have isolated the recessive medaka mutation tintachina (tch), which carries an inactivating modification of the conserved glycine residue (G75R) of the proton pump subunit atp6v1Ba/vatB1. Mutant embryos show penetrant pigmentation defects,...

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Identifiers

PMID: 24225653
DOI: 10.1038/srep03217
PMCID: PMC3827601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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