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Article

The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population.

Disease markers - 1 Jan 2013

Elhawary Nasser Attia, Hewedi Doaa, Arab Arwa, Teama Salwa, Shaibah Hassan, Tayeb Mohammed Taher, Bogari Neda

Abstract excerpt

OBJECTIVE: We evaluated whether the methylenetetrahydrofolate reductase (MTHFR) 677C>T marker influences the risk and severity of Alzheimer's disease (AD) and whether AD is associated with homocysteine, vitamin B12, and cholesterol levels in Egypt. METHODS: Forty-three Alzheimer's cases and 32 non-AD controls were genotyped for the 677C>T polymorphism. Clinical characteristics and levels of homocysteine, vitamin...

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Source

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Identifiers

PMID: 24223459
DOI: 10.1155/2013/524106
PMCID: PMC3810363

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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