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Article

Gene Network and Proteomic Analyses of Cardiac Responses to Pathological and Physiological Stress

9 Nov 2013

Abstract excerpt

BACKGROUND: The molecular mechanisms underlying similarities and differences between physiological and pathological left ventricular hypertrophy (LVH) are of intense interest. Most previous work involved targeted analysis of individual signaling pathways or screening of transcriptomic profiles. We developed a network biology approach using genomic and proteomic data to study the molecular patterns that...

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PMID: 24214729
DOI: 10.1161/circgenetics.113.000063

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