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Concise Review: Leukemia Stem Cells in Personalized Medicine

8 Nov 2013

Abstract excerpt

Despite increased comprehension of acute myelogenous leukemia (AML) pathogenesis, current treatment strategies have done little to improve upon standard induction chemotherapy to induce long-term remissions. Since the identification of the leukemic stem cell, efforts have been placed on identifying therapeutically actionable pathways that distinguish this increasingly important cellular compartment. With the...

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PMID: 24214290
DOI: 10.1002/stem.1597

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