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Article

Emerging Roles of ADAMTSs in Angiogenesis and Cancer

29 Nov 2012

Abstract excerpt

A Disintegrin-like And Metalloproteinase with ThromboSpondin motifs-ADAMTSs-are a multi-domain, secreted, extracellular zinc metalloproteinase family with 19 members in humans. These extracellular metalloproteinases are known to cleave a wide range of substrates in the extracellular matrix. They have been implicated in various physiological processes, such as extracellular matrix turnover, melanoblast...

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PMID: 24213506
DOI: 10.3390/cancers4041252

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