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Article

CAMKIIγ, HSP70 and HSP90 transcripts are differentially expressed in chronic myeloid leukemia cells from patients with resistant mutated disease.

Leukemia & lymphoma - 1 Sept 2014

Gonzalez Mariana, De Brasi Carlos, Ferri Cristian, Bengió Raquel, Bianchini Michele, Larripa Irene

Abstract excerpt

Patients with chronic myeloid leukemia (CML) can develop disease resistance to tyrosine kinase inhibitor (TKI) therapy, which is mainly attributable to the presence of point mutations in the tyrosine kinase domain of BCR-ABL1. In order to examine suitable markers to monitor treatment efficacy, we investigated transcript expression profiles of genes known to be involved in myeloid cell proliferation, such as...

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Share to Calcium-Calmodulin-Dependent Protein Kinase Type 2
Share to Fusion Proteins, bcr-abl

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to HSP70 Heat-Shock Proteins

Share to HSP90 Heat-Shock Proteins

Share to Ki-67 Antigen

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Protein Interaction Domains and Motifs

Source

Identifiers

PMID: 24206096
DOI: 10.3109/10428194.2013.861070

Genes

ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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