Article
Genetic variations in cytotoxic T-lymphocyte antigen-4 and susceptibility to cervical cancer.
International immunopharmacology - 1 Jan 2014
Xiong Yuan-Huan, He Li, Fei Jing
Abstract excerpt
Cytotoxic T-lymphocyte antigen-4 (CTLA-4), a molecule expressed predominantly on activated T cells, plays an important role in the down-regulation of T-cell activation. To evaluate the potential effects of CTLA-4 gene polymorphisms on susceptibility to cervical cancer, we genotyped polymorphisms in CTLA-4 (- 318 T/C, CT60 G/A,+49 G/A, - 658 T/C, and - 1661 G/A) and calculated odds ratios for the genotype and...
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