Article
[Association between CTLA-4 gene polymorphism and susceptibility to cervical cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 2011
Li Hua, Zhou Yi-feng, Guo Hong-yan, Sun Tong, Zhang Wen-hua, Lin Dong-xin
Abstract excerpt
OBJECTIVE: To investigate the association between CTLA-4 +49A/G polymorphisms and the risk of susceptibility to cervical cancer. METHODS: A hospital-based case-control study was conducted. 314 cases with primary cervical cancer and 320 healthy controls were collected and genotyped by PCR-based RFLP for +49A/G polymorphisms in the CTLA-4 gene. RESULTS: The A allele and AA genotype of CTLA-4 gene were 32.5% and...
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