Article
[Construction of aerobactin and sit operon mutant of avian pathogenic Escherichia coli E058 and evaluation of its pathogenicity].
Wei sheng wu xue bao = Acta microbiologica Sinica - 4 Jul 2013
Ling Jielu, Chen Siyi, Gao Qingqing, Xu Huiqing, Gao Song, Liu Xiufan
Abstract excerpt
OBJECTIVE: To elucidate the pathogenesis role of the vir region of APEC 02 strain E058. METHODS: The gene aerobactin/sitABC operon knockout mutants E058deltavir of APEC E058 strain was generated using Red recombination system. A series of pathogenicity tests including chick embryo inoculation, the competition experiment and the colonization and persistence in vivo were used to evaluate the pathogenicity of APEC...
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