Article
Inductive ability of human developing and differentiated dental mesenchyme.
Cells, tissues, organs - 1 Jan 2013
Zheng Liwei, Warotayanont Rungnapa, Stahl Jonathan, Kunimatsu Ryo, Klein Ophir, DenBesten Pamela K, Zhang Yan
Abstract excerpt
The development of cell-based therapeutic strategies to bioengineer tooth tissue is a promising approach for the treatment of lost or damaged tooth tissue. The lack of a readily available cell source for human dental epithelial cells (ECs) severely constrains the progress of tooth bioengineering. Previous studies in model organisms have demonstrated that developing dental mesenchyme can instruct nondental...
Topics
- Adult
- Ameloblasts
- Amelogenin
- Animals
- Cell Differentiation
- Cell Lineage
- Embryonic Stem Cells
- Epithelial Cells
- Epithelium
- Fetus
- Humans
- Lymphoid Enhancer-Binding Factor 1
- Male
- Mesoderm
- Mice