Article
The similarity between human embryonic stem cell-derived epithelial cells and ameloblast-lineage cells.
International journal of oral science - 1 Mar 2013
Zheng Li-Wei, Linthicum Logan, DenBesten Pamela K, Zhang Yan
Abstract excerpt
This study aimed to compare epithelial cells derived from human embryonic stem cells (hESCs) to human ameloblast-lineage cells (ALCs), as a way to determine their potential use as a cell source for ameloblast regeneration. Induced by various concentrations of bone morphogenetic protein 4 (BMP4), retinoic acid (RA) and lithium chloride (LiCl) for 7 days, hESCs adopted cobble-stone epithelial phenotype...
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