Article
CXCR4 pathway associated with family history of melanoma.
Cancer causes & control : CCC - 1 Jan 2014
Li Wen-Qing, Han Jiali, Widlund Hans R, Correll Mick, Wang Yaoyu E, Quackenbush John, Mihm Martin C, Canales Alvaro Laga, Wu Shaowei, Golub Todd, Hoshida Yujin, Hunter David J, Murphy George, Kupper Thomas S, Qureshi Abrar A
Abstract excerpt
PURPOSE: Genetic predisposition plays a major role in the etiology of melanoma, but known genetic markers only account for a limited fraction of family-history-associated melanoma cases. Expression microarrays have offered the opportunity to identify further genomic profiles correlated with family history of melanoma. We aimed to distinguish mRNA expression signatures between melanoma cases with and without a...
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