Article
Mouse model phenotypes provide information about human drug targets.
Bioinformatics (Oxford, England) - 1 Mar 2014
Hoehndorf Robert, Hiebert Tanya, Hardy Nigel W, Schofield Paul N, Gkoutos Georgios V, Dumontier Michel
Abstract excerpt
MOTIVATION: Methods for computational drug target identification use information from diverse information sources to predict or prioritize drug targets for known drugs. One set of resources that has been relatively neglected for drug repurposing is animal model phenotype. RESULTS: We investigate the use of mouse model phenotypes for drug target identification. To achieve this goal, we first integrate mouse model...
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