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Newborns of obese parents have altered DNA methylation patterns at imprinted genes

25 Oct 2013

Abstract excerpt

BACKGROUND: Several epidemiologic studies have demonstrated associations between periconceptional environmental exposures and health status of the offspring in later life. Although these environmentally related effects have been attributed to epigenetic changes, such as DNA methylation shifts at imprinted genes, little is known about the potential effects of maternal and paternal preconceptional overnutrition or...

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PMID: 24158121
DOI: 10.1038/ijo.2013.193

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