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Article

Impact of climate factors and climate-gene interaction on systemic lupus erythematosus patients' response to glucocorticoids therapy.

Journal of clinical laboratory analysis - 1 Jul 2023

Zhang Tingyu, Xie Qiaomei, Wang Linlin, Wang Yuhua, Yan Ziye, Li Zhen, Teng Ying, Xu Zhiwei, Chen Yangfan, Pan Faming, Tao Jinhui, Cai Jing, Liang Chunmei, Pan Haifeng, Su Hong, Cheng Jian, Hu Wenbiao, Zou Yanfeng

Abstract excerpt

BACKGROUND: Glucocorticoids (GCs) were the essential drugs for systemic lupus erythematosus (SLE). However, different patients differ substantially in their response to GCs treatment. Our current study aims at investigating whether climate variability and climate-gene interaction influence SLE patients' response to the therapy of GCs. METHODS: In total, 778 SLE patients received therapy of GCs for a study of...

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Identifiers

PMID: 37488812
DOI: 10.1002/jcla.24945
PMCID: PMC10492452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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