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Article

Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 5 Nov 2013

Oud Bart, Guadalupe-Medina Victor, Nijkamp Jurgen F, de Ridder Dick, Pronk Jack T, van Maris Antonius J A, Daran Jean-Marc

Abstract excerpt

Laboratory evolution of the yeast Saccharomyces cerevisiae in bioreactor batch cultures yielded variants that grow as multicellular, fast-sedimenting clusters. Knowledge of the molecular basis of this phenomenon may contribute to the understanding of natural evolution of multicellularity and to manipulating cell sedimentation in laboratory and industrial applications of S. cerevisiae. Multicellular,...

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Identifiers

PMID: 24145419
DOI: 10.1073/pnas.1305949110
PMCID: PMC3831460

Genes

ACE2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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