Article
Oxidized alginate hydrogels as niche environments for corneal epithelial cells.
Journal of biomedical materials research. Part A - 1 Oct 2014
Wright Bernice, De Bank Paul A, Luetchford Kim A, Acosta Fernando R, Connon Che J
Abstract excerpt
Chemical and biochemical modification of hydrogels is one strategy to create physiological constructs that maintain cell function. The aim of this study was to apply oxidised alginate hydrogels as a basis for development of a biomimetic niche for limbal epithelial stem cells that may be applied to treating corneal dysfunction. The stem phenotype of bovine limbal epithelial cells (LEC) and the viability of corneal...
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