Article
Assessing the detection of human papillomavirus late mRNA in liquid base cytology samples for risk stratification of cervical disease.
Journal of medical virology - 1 Apr 2014
Chambers George, Millan David, Cuschieri Kate, Cubie Heather A, Graham Sheila V
Abstract excerpt
Molecular human papillomavirus (HPV) testing is an important and developing tool for cervical disease management. However there is a requirement to develop new HPV tests that can differentiate between clinically significant and benign, clinically insignificant infection. Evidence would indicate that clinically significant infection is linked to an abortive HPV replication cycle. In particular the later stages of...
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