Article
Approaching the increasing complexity of non-small cell lung cancer taxonomy.
Current pharmaceutical design - 1 Jan 2014
Maugeri-Sacca Marcello, Bartucci Monica, Pagliuca Alfredo, Patrizii Michele, Signore Michele, De Maria Ruggero
Abstract excerpt
The advent of molecular targeted agents is changing the treatment of solid tumors. In non-small-cell lung cancer, compounds directed against oncogenic proteins offer novel therapeutic opportunities for a fraction of patients whose tumors harbor specific genetic defects. With the increased level of resolution achieved by high-throughput technologies, the taxonomy of lung cancer is rapidly changing. For instance,...
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