Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative omics approach identifies interleukin-16 as a biomarker of emphysema.

Omics : a journal of integrative biology - 1 Dec 2013

Bowler Russell P, Bahr Timothy M, Hughes Grant, Lutz Sharon, Kim Yu-Il, Coldren Christopher D, Reisdorph Nichole, Kechris Katerina J

Abstract excerpt

Interleukin-16 (IL-16) is a multifunctional cytokine that has been associated with autoimmune and allergic diseases. To investigate comprehensively whether IL-16 is also associated with chronic obstructive pulmonary disease (COPD) and emphysema, we performed an integrated analysis of multiple "omics" data. Over 500 subjects participating in the COPDGene® study donated blood and were clinically characterized and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Cortex Hormones
Share to Emphysema

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-16

Share to Leukocytes, Mononuclear

Share to Proteomics

Share to Pulmonary Disease, Chronic Obstructive

Share to Quantitative Trait Loci

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 24138069
DOI: 10.1089/omi.2013.0038
PMCID: PMC3837437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative omics approach identifies interleukin-16 as a biomarker of emphysema.PMID 24138069Read ↗

A protective polymorphism in MMP16, improved blood gas levels, and chronic obstructive pulmonary diseases: Family and two population-based studies.Semantic proximity Read ↗

Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD.Semantic proximity Read ↗

Blood-Based Transcriptomic and Proteomic Biomarkers of EmphysemaSemantic proximity Read ↗

Integrative omics analysis identifies biomarkers of idiopathic pulmonary fibrosisSemantic proximity Read ↗

lnterleukin-16: The Ins and Outs of Regulating T-Cell ActivationSemantic proximity Read ↗

Association between single-nucleotide polymorphism of cytokines genes and chronic obstructive pulmonary disease: A systematic review and meta-analysis.Semantic proximity Read ↗

Cytokines mapping for tissue-specific expression, eQTLs and GWAS traits.Semantic proximity Read ↗

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.Semantic proximity Read ↗

GA-binding protein factors, in concert with the coactivator CREB binding protein/p300, control the induction of the interleukin 16 promoter in T lymphocytesSemantic proximity Read ↗

Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.Semantic proximity Read ↗

Identification of CXCL16 as Diagnostic Biomarker Related to Obesity and Intervertebral Disc Degeneration based on Machine LearningSemantic proximity Read ↗

Target genes regulated by CLEC16A intronic region associated with common variable immunodeficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.