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Article

Role of JunB in adenosine A2B receptor-mediated vascular endothelial growth factor production.

Molecular pharmacology - 1 Jan 2014

Ryzhov Sergey, Biktasova Asel, Goldstein Anna E, Zhang Qinkun, Biaggioni Italo, Dikov Mikhail M, Feoktistov Igor

Abstract excerpt

Interstitial adenosine stimulates neovascularization in part through A2B adenosine receptor-dependent upregulation of vascular endothelial growth factor (VEGF). In the current study, we tested the hypothesis that A2B receptors upregulate JunB, which can contribute to stimulation of VEGF production. Using the human microvascular endothelial cell line, human mast cell line, mouse cardiac Sca1-positive stromal...

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Share to Adenosine
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Share to Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Transcription Factor AP-1

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Identifiers

PMID: 24136993
DOI: 10.1124/mol.113.088567
PMCID: PMC3868903

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