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Article

Statistical and practical considerations for clinical evaluation of predictive biomarkers.

Journal of the National Cancer Institute - 20 Nov 2013

Polley Mei-Yin C, Freidlin Boris, Korn Edward L, Conley Barbara A, Abrams Jeffrey S, McShane Lisa M

Abstract excerpt

Predictive biomarkers to guide therapy for cancer patients are a cornerstone of precision medicine. Discussed herein are considerations regarding the design and interpretation of such predictive biomarker studies. These considerations are important for both planning and interpreting prospective studies and for using specimens collected from completed randomized clinical trials. Specific issues addressed are...

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Identifiers

PMID: 24136891
DOI: 10.1093/jnci/djt282
PMCID: PMC3888208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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