Article
Decoding the pathophysiology and the genetics of multiple myeloma to identify new therapeutic targets.
Seminars in oncology - 1 Oct 2013
Lawasut Panisinee, Groen Richard W J, Dhimolea Eugen, Richardson Paul G, Anderson Kenneth C, Mitsiades Constantine S
Abstract excerpt
In recent years, significant progress has been achieved in the characterization of the transcriptional profiles, gene mutations and structural chromosomal lesions in myeloma cells. These studies have identified many candidate therapeutic targets, which are recurrently deregulated in myeloma cells. However, these targets do not appear, at least individually, to represent universal driver(s) of this disease....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.