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Article

Going with the Flow: From Circulating Tumor Cells to DNA

16 Oct 2013

Abstract excerpt

Molecular analyses of circulating tumor DNA (ctDNA) in plasma from cancer patients have the potential to deliver minimally invasive diagnostic and disease-monitoring biomarkers. Drawing from experience gained through the translation of circulating tumor cell detection to clinical tests, we discuss ctDNA as a source of tumor material for biomarker development.

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Identifiers

PMID: 24132635
DOI: 10.1126/scitranslmed.3006305

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