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Article

Folate intake and MTHFR polymorphism C677T is not associated with ovarian cancer risk: evidence from the meta-analysis.

Molecular biology reports - 1 Dec 2013

Li Chenglin, Chen Peizhan, Hu Pingting, Li Mian, Li Xiaoguang, Guo He, Li Jingquan, Chu Ruiai, Zhang Wei, Wang Hui

Abstract excerpt

Folate is essential for DNA synthesis and methylation and implicated in the process of carcinogenesis. Several studies inconclusively suggested increased folate intake may reduce ovarian cancer risk. Studies concerning the association between C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR), an important enzyme in folate metabolism, and ovarian cancer risk also resulted in no agreement. The...

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Source

Identifiers

PMID: 24129496
DOI: 10.1007/s11033-013-2686-0

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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