Article
Secondary lymphoid organ homing phenotype of human myeloid dendritic cells disrupted by an intracellular oral pathogen.
Infection and immunity - 1 Jan 2014
Miles Brodie, Zakhary Ibrahim, El-Awady Ahmed, Scisci Elizabeth, Carrion Julio, O'Neill John C, Rawlings Aaron, Stern J Kobi, Susin Cristiano, Cutler Christopher W
Abstract excerpt
Several intracellular pathogens, including a key etiological agent of chronic periodontitis, Porphyromonas gingivalis, infect blood myeloid dendritic cells (mDCs). This infection results in pathogen dissemination to distant inflammatory sites (i.e., pathogen trafficking). The alteration in chemokine-chemokine receptor expression that contributes to this pathogen trafficking function, particularly toward sites of...
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