Article
Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas.
Cell reports - 31 Oct 2013
Tsai Ming-Han, Raykova Ana, Klinke Olaf, Bernhardt Katharina, Gärtner Kathrin, Leung Carol S, Geletneky Karsten, Sertel Serkan, Münz Christian, Feederle Regina, Delecluse Henri-Jacques
Abstract excerpt
The Epstein-Barr virus (EBV) is found in a variety of tumors whose incidence greatly varies around the world. A poorly explored hypothesis is that particular EBV strains account for this phenomenon. We report that M81, a virus isolated from a Chinese patient with nasopharyngeal carcinoma (NPC), shows remarkable similarity to other NPC viruses but is divergent from all other known strains. M81 exhibited a reversed...
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