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Article

Viral and host factors drive a type 1 Epstein-Barr virus spontaneous lytic phenotype.

mBio - 19 Dec 2023

Willard Katherine A, Barry Ashley P, Oduor Cliff I, Ong'echa John Michael, Bailey Jeffrey A, Moormann Ann M, Luftig Micah A

Abstract excerpt

IMPORTANCE: Epstein-Barr virus (EBV) infects over 95% of adults worldwide. Given its connection to various cancers and autoimmune disorders, it is important to understand the mechanisms by which infection with EBV can lead to these diseases. In this study, we describe an unusual spontaneous lytic phenotype in EBV strains isolated from Kenyan endemic Burkitt lymphoma patients. Because lytic replication of EBV has...

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Identifiers

PMID: 37971257
DOI: 10.1128/mbio.02204-23
PMCID: PMC10746244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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