Article
Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs.
Journal of internal medicine - 1 Mar 2014
Pereira J B, Cavallin L, Spulber G, Aguilar C, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Aarsland D, Lovestone S, Simmons A, Wahlund L-O, Westman E
Abstract excerpt
BACKGROUND: Visual assessment of medial temporal lobe atrophy (MTA; range 0-4, from no atrophy to increasing atrophy of the choroid fissure, temporal horns and hippocampus) is a sensitive radiological marker of Alzheimer's disease (AD). One of the critical elements for visual MTA assessment is the cut-off score that determines deviation from normality. METHODS: In this study, we assessed the sensitivity and...
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