Article
RNA-Seq reveals differential gene expression in Staphylococcus aureus with single-nucleotide resolution.
PloS one - 1 Jan 2013
Osmundson Joseph, Dewell Scott, Darst Seth A
Abstract excerpt
Staphylococcus aureus is a gram-positive cocci and an important human commensal bacteria and pathogen. S. aureus infections are increasingly difficult to treat because of the emergence of highly resistant MRSA (methicillin-resistant S. aureus) strains. Here we present a method to study differential gene expression in S. aureus using high-throughput RNA-sequencing (RNA-seq). We used RNA-seq to examine gene...
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