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Article

Association of polycystic ovarian syndrome with inflammatory single nucleotide polymorphism for IL-1 & IL-6 genes: A case-control study.

The Indian journal of medical research - 1 Dec 2025

Benjamin Jiby Jolly, Ramaswamy Padmavathi, Kuppusamy Mahesh Kumar, Vembu Radha, Rajamani Karthikeyan, Puttaswamy Naveen, Narayanasa Maruthy Kalburgi, Mathews Rahul Rajan, Koshy Teena

Abstract excerpt

Background & objectives Persistent mild inflammation is considered as a main contributor to the altered genesis of polycystic ovary syndrome (PCOS), with numerous studies reporting elevated serum levels of inflammatory markers. This inflammatory state may be attributed to genetic variants, particularly single nucleotide polymorphisms (SNP), that alter cytokine regulation. This study investigated the association...

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Identifiers

PMID: 41648974
DOI: 10.25259/IJMR_1499_2025
PMCID: PMC12883111

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TNF

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