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Adaptations of placental and cord blood<i>ABCA1 </i>DNA methylation profile to maternal metabolic status

10 Oct 2013

Abstract excerpt

In utero environmental perturbations have been associated with epigenetic changes in the offspring and a lifelong susceptibility to cardiovascular diseases (CVD). DNA methylation at the ATP-binding cassette transporter A1 (ABCA1) gene was previously associated with CVD, but whether these epigenetic marks respond to changes in the maternal environment is unknown. This study was undertaken to assess the...

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PMID: 24113149
DOI: 10.4161/epi.26554

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