Article
Antibacterial mechanisms identified through structural systems pharmacology.
BMC systems biology - 10 Oct 2013
Chang Roger L, Xie Lei, Bourne Philip E, Palsson Bernhard O
Abstract excerpt
BACKGROUND: The growing discipline of structural systems pharmacology is applied prospectively in this study to predict pharmacological outcomes of antibacterial compounds in Escherichia coli K12. This work builds upon previously established methods for structural prediction of ligand binding poc...
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