Article
Risk assessment of multistate progression of breast tumor with state-dependent genetic and environmental covariates.
Risk analysis : an official publication of the Society for Risk Analysis - 1 Feb 2014
Wu Yi-Ying, Yen Ming-Fang, Yu Cheng-Ping, Chen Hsiu-Hsi
Abstract excerpt
Few studies have focused on the different roles risk factors play in the multistate temporal natural course of breast cancer. We proposed a three-state Markov regression model to predict the risk from free of breast cancer (FBC) to the preclinical screen-detectable phase (PCDP) and from the PCDP to the clinical phase (CP). We searched the initiators and promoters affecting onset and subsequent progression of...
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