SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength.

doi:10.2337/db13-1150

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SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength.

Diabetes - 1 Jan 2014

Sprouse Courtney, Gordish-Dressman Heather, Orkunoglu-Suer E Funda, Lipof Jason S, Moeckel-Cole Stephanie, Patel Ronak R, Adham Kasra, Larkin Justin S, Hubal Monica J, Kearns Amy K, Clarkson Priscilla M, Thompson Paul D, Angelopoulos Theodore J, Gordon Paul M, Moyna Niall M, Pescatello Linda S, Visich Paul S, Zoeller Robert F, Hoffman Eric P, Tosi Laura L, Devaney Joseph M

Abstract excerpt

Genome-wide association studies have identified thousands of variants that are associated with numerous phenotypes. One such variant, rs13266634, a nonsynonymous single nucleotide polymorphism in the solute carrier family 30 (zinc transporter) member eight gene, is associated with a 53% increase in the risk of developing type 2 diabetes (T2D). We hypothesized that individuals with the protective allele against...

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PMID: 24101675
DOI: 10.2337/db13-1150

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