Article
A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes.
Diabetes - 1 Jan 2014
Hanson Robert L, Muller Yunhua L, Kobes Sayuko, Guo Tingwei, Bian Li, Ossowski Victoria, Wiedrich Kim, Sutherland Jeffrey, Wiedrich Christopher, Mahkee Darin, Huang Ke, Abdussamad Maryam, Traurig Michael, Weil E Jennifer, Nelson Robert G, Bennett Peter H, Knowler William C, Bogardus Clifton, Baier Leslie J
Abstract excerpt
Most genetic variants associated with type 2 diabetes mellitus (T2DM) have been identified through genome-wide association studies (GWASs) in Europeans. The current study reports a GWAS for young-onset T2DM in American Indians. Participants were selected from a longitudinal study conducted in Pima Indians and included 278 cases with diabetes with onset before 25 years of age, 295 nondiabetic controls ≥45 years of...
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