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Prognostic value of mitochondrial DNA content and G10398A polymorphism in non-small cell lung cancer

3 Oct 2013

Abstract excerpt

Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related mortality worldwide. Mitochondrial dysfunction has been postulated to render cancer cells resistant to apoptosis based on the Warburg hypothesis. However, few studies have investigated the prognostic value of mitochondrial DNA (mtDNA) content and G10398A polymorphism in NSCLC patients. mtDNA copy number and G10398A polymorphism in...

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PMID: 24101028
DOI: 10.3892/or.2013.2783

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