Article
Dopamine receptor 4 promoter polymorphism modulates memory and neuronal responses to salience.
NeuroImage - 1 Jan 2014
Strange B A, Gartmann N, Brenninkmeyer J, Haaker J, Reif A, Kalisch R, Büchel C
Abstract excerpt
Animal models and human functional imaging data implicate the dopamine system in mediating enhanced encoding of novel stimuli into human memory. A separate line of investigation suggests an association between a functional polymorphism in the promoter region for the human dopamine 4 receptor gene (DRD4) and sensitivity to novelty. We demonstrate, in two independent samples, that the -521C>T DRD4 promoter...
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