A conditional predictive p-value to compare a multinomial with an overdispersed multinomial in the analysis of T-cell populations.

Abstract excerpt

Immunological experiments that record primary molecular sequences of T-cell receptors produce moderate to high-dimensional categorical data, some of which may be subject to extra-multinomial variation caused by technical constraints of cell-based assays. Motivated by such experiments in melanoma research, we develop a statistical procedure for testing the equality of two discrete populations, where one population...

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